Statistical Issues in Life Course Epidemiology
نویسندگان
چکیده
منابع مشابه
Statistical issues in life course epidemiology.
There is growing recognition that the risk of many diseases in later life, such as type 2 diabetes or breast cancer, is affected by adult as well as early-life variables, including those operating prior to conception and during the prenatal period. Most of these risk factors are correlated because of common biologic and/or social pathways, while some are intrinsically ordered over time. The stu...
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1 Department of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, London, United Kingdom. 2 MRC National Survey of Health and Development, Department of Epidemiology, Royal Free and University College Medical School, London, United Kingdom. 3 Centre for Paediatric Epidemiology and Biostatistics, Institute of Child Health, University College London, London, Unit...
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Like many other fields, psychiatric researchers rely heavily on the utilization of conventional epidemiologic designs and principles to pursue their scientific objectives. However, some of the issues, which to a large extent are specific to psychiatric disorders, have demanded that new designs and hence new statistical methods be developed to meet the challenges. These issues include, among oth...
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Life-course epidemiology seeks to better understand the mechanisms that lead to the development of chronic diseases. An example is the mechanism leading from body size to coronary heart disease (CHD); one way to acquire a better understanding of this mechanism is to investigate to what extent it works through other risk factors. In this paper, the dynamic path analysis model is presented as a t...
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There has been a traditional view that divided epidemiology into infectious and chronic diseases. Since we now know that at least 15% of cancers worldwide are caused by infections, 1 that infections frequently have a natural history lasting decades and that the same epidemiological methods can be applied to both infectious and non-infectious diseases, this view can be considered purely historic...
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ژورنال
عنوان ژورنال: American Journal of Epidemiology
سال: 2005
ISSN: 1476-6256,0002-9262
DOI: 10.1093/aje/kwj003